Plenary Speakers

• Fellow Member Professor of
  Biomedical Engineering at Vanderbilt Univ
• SPIE President
• SPIE Membership: 5 years
• SPIE Awards: Fellow status | 2019 SPIE Community Champion
• SPIE Involvement: Board of Directors | Compensation Committee | Strategic Planning Committee | Executive Committee | Conference Program Committee | Track Chair | Author | Editor | Student Chapter Advisor
• Area of Expertise: Optical Spectroscopy, Optical Imaging, Optical Stimulation, Biomedical Optics, Optical Diagnosis, Optical Guidance of Therapy

Publication:

1. E Haugen, GA Throckmorton, AB Walter, Z Guo, JS Baba, ..., "Ex vivo determination of nerve and surrounding tissue optical properties in rats and human cadavers for nerve-sparing surgical applications," Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX …, 2022.
2. GA Throckmorton, E Haugen, J Baba, C Solórzano, A Mahadevan-Jansen, "Spectral imaging for intraoperative nerve visualization during thyroid surgery," Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX …, 2022.
3. G Thomas, CM Kiernan, A Mahadevan-Jansen, CC Solórzano, "Is near infrared autofluorescence detection beneficial for parathyroidectomies? A randomized single center clinical trial," Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX …, 2022.
4. WR Adams, R Gautam, A Locke, LE Masson, AI Borrachero-Conejo, ..., "Visualizing the lipid dynamics role in infrared neural stimulation using stimulated Raman scattering," Biophysical Journal, 2022.
5. AS Rourke, L Masson, T Voss, B Hitchcock, A Burston, ..., "Spatially offset Raman spectroscopy for non-invasive in vivo monitoring of hydration status," Biophotonics in Exercise Science, Sports Medicine, Health Monitoring …, 2022.
6. MH Nguyen, CA Oian, A Mahadevan-Jansen, ED Jansen, "Computational modeling of photomechanical effects during infrared neural stimulation," Optogenetics and Optical Manipulation 2022, PC1194707, 2022.
7. A Mahadevan-Jansen, "Translation of a label-free approach to surgical guidance," Molecular-Guided Surgery: Molecules, Devices, and Applications VIII, PC1194301, 2022.
8. GA Throckmorton, ED Jansen, A Mahadevan-Jansen, "Comparing electrical and infrared neural stimulation for intraoperative nerve monitoring," Optogenetics and Optical Manipulation 2022, PC1194702, 2022.
9. F Zaki, A Locke, S Fitzgerald, K Sudhir, GL Monroy, H Choi, J Won, ..., "Non-invasive detection and characterization of otitis media causing bacteria and bacterial biofilms through Raman spectroscopy and optical coherence tomography," Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and …, 2022.
10. SD Tripathi, ST Fitzgerald, G Thomas, JR Shinn, CB Wood, YJ Kim, ..., "Feasibility of Raman spectroscopy to characterize and detect oropharyngeal cancer," Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry …, 2022.
11. G Thomas, PA Willmon, R Belcher, M Lopez, HN Lovvorn III, ..., "Label-free parathyroid gland identification during pediatric neck surgeries with near infrared autofluorescence detection," Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and …, 2022.
12. LE Masson, CM O’Brien, R Gautam, G Thomas, JC Slaughter, M Goldberg, ..., "In vivo Raman spectroscopy monitors cervical change during labor," American Journal of Obstetrics and Gynecology, 2022.
13. EA Mannoh, A Mahadevan-Jansen, "Combined fluorescence and laser speckle contrast imaging system and applications of same," US Patent App. 17/289,323, 2022.
14. G Thomas, CC Solórzano, N Baregamian, EA Mannoh, R Gautam, ..., "Comparing intraoperative parathyroid identification based on surgeon experience versus near infrared autofluorescence detection–A surgeon-blinded multi-centric study," The American Journal of Surgery 222 (5), 944-951, 2021.
15. MA Al Mamun, PR Stoddart, A Mahadevan-Jansen, NA Cole, "Optical fibre based microprobe," US Patent 11,156,555, 2021.
16. EA Mannoh, G Thomas, N Baregamian, SL Rohde, CC Solórzano, ..., "Assessing intraoperative laser speckle contrast imaging of parathyroid glands in relation to total thyroidectomy patient outcomes," Thyroid 31 (10), 1558-1565, 2021.
17. M Zhao, Q Liu, A Jha, R Deng, T Yao, A Mahadevan-Jansen, MJ Tyska, ..., "VoxelEmbed: 3D instance segmentation and tracking with voxel embedding based deep learning," International Workshop on Machine Learning in Medical Imaging, 437-446, 2021.
18. M Zhao, A Jha, Q Liu, BA Millis, A Mahadevan-Jansen, L Lu, BA Landman, ..., "Faster mean-shift: GPU-accelerated clustering for cosine embedding-based cell segmentation and tracking," Medical Image Analysis 71, 102048, 2021.
19. Q Liu, IM Gaeta, M Zhao, R Deng, A Jha, BA Millis, A Mahadevan-Jansen, ..., "ASIST: Annotation-free synthetic instance segmentation and tracking by adversarial simulations," Computers in Biology and Medicine 134, 104501, 2021.
20. A Abbas, M McWade, A Mahadevan-Jansen, "Optical overlay device," US Patent App. 17/204,439, 2021.
21. LE Masson, R Gautam, A Locke, G Thomas, A Mahadevan-Jansen, "Combined fingerprint and high wavenumber spatially offset Raman spectroscopy for depth-resolved hydration and biochemical assessment," European Conference on Biomedical Optics, EW3A. 1, 2021.
22. C O'brien, K Cochran, A Mahadevan-Jansen, KR Findley, W Stokes, ..., "Method, system and speculum-free optical probe for optical assessment of cervix, and applications of same," US Patent App. 16/613,445, 2021.
23. EA Mannoh, LB Parker, G Thomas, CC Solórzano, A Mahadevan‐Jansen, "Development of an imaging device for label‐free parathyroid gland identification and vascularity assessment," Journal of Biophotonics 14 (6), e202100008, 2021.
24. WR Adams, B Mehl, E Lieser, M Wang, S Patton, GA Throckmorton, ..., "Multi-modal nonlinear optical and thermal imaging platform for label-free characterization of biological tissue," Scientific reports 11 (1), 1-13, 2021.
25. JC Snider, LA Riley, NT Mallory, MR Bersi, P Umbarkar, R Gautam, ..., "Targeting 5-HT2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling After Myocardial Infarction," Circulation 143 (13), 1317-1330, 2021.
26. A Mahadevan-Jansen, "Multi-Modal Microscope for Biophysical Assessment of Optical Perturbation in the Neural System," Vanderbilt University, 2021.
27. AM Mahadevan-Jansen, "Translating spectroscopy for clinical care," Optical Tomography and Spectroscopy of Tissue XIV 11639, 1163903, 2021.
28. EA Mannoh, LB Parker, G Thomas, CC Solórzano, ..., "A multimodal imaging system for label-free parathyroid gland identification and vascularity assessment," Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems …, 2021.
29. AI Borrachero-Conejo, WR Adams, GA Throckmorton, JL Jenkins, ..., "Stimulation of Schwann cells by infrared pulsed stimulation," Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics 11629 …, 2021.
30. AI Borrachero-Conejo, WR Adams, E Saracino, T Posati, MG Mola, ..., "Infrared modulation of ionic and water dynamics of astroglial cells," Optical Interactions with Tissue and Cells XXXII 11640, 116400A, 2021.
31. G Thomas, E Mannoh, ME Sanders, CM Kiernan, N Baregamian, ..., "Assessing a fiber probe-based approach to detect near infrared fluorescence for identifying and preserving parathyroid glands during neck surgeries," Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems …, 2021.
32. AK Locke, G Hiremath, R Tyree, A Mahadevan-Jansen, "Saliva characterization of eosinophilic esophagitis via surface enhanced Raman spectroscopy," Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics 11651 …, 2021.
33. GA Throckmorton, JS Baba, A Mahadevan-Jansen, "Multimodal intrinsic contrast imaging for nerve discrimination in vivo," Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems …, 2021.
34. S Fitzgerald, A Locke, A Mahadevan-Jansen, O Ayala, "Non-invasive detection and characterization of Otitis Media with Raman spectroscopy," Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems …, 2021.
35. JL Jenkins, WR Adams, JB Ford, S Evans, AM Mahadevan-Jansen, ..., "Laser-induced heating modulates microglial calcium signaling," Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics 11629 …, 2021.
36. G Throckmorton, J Cayce, Z Ricks, WR Adams, ED Jansen, ..., "Identifying optimal parameters for infrared neural stimulation in the peripheral nervous system," Neurophotonics 8 (1), 015012, 2021.
37. A Mahadevan-Jansen, OD Ayala, EP Skaar, CA Wakeman, ..., "Methods and systems for identification of bacteria in biological fluid using raman spectroscopy and applications of same," US Patent 10,914,683, 2021.
38. L Masson, C O'Brien, JMM Netwon, E Elsamadicy, A Mahadevan-Jansen, "569 A novel technique using raman spectroscopy for assessing cervical change during labor," American Journal of Obstetrics & Gynecology 224 (2), S360, 2021.
39. IJ Pence, CM O’Brien, LE Masson, A Mahadevan-Jansen, "Application driven assessment of probe designs for Raman spectroscopy," Biomedical Optics Express 12 (2), 852-871, 2021.
40. M Unal, R Ahmed, A Mahadevan-Jansen, JS Nyman, "Compositional assessment of bone by Raman spectroscopy," Analyst 146 (24), 7464-7490, 2021.
41. Q Liu, IM Gaeta, M Zhao, R Deng, A Jha, BA Millis, A Mahadevan-Jansen, ..., "Towards annotation-free instance segmentation and tracking with adversarial simulations," arXiv e-prints, arXiv: 2101.00567, 2021.
42. WR Adams, R Gautam, A Locke, AI Borrachero-Conejo, B Dollinger, ..., "Visualizing the Role of Lipid Dynamics during Infrared Neural Stimulation with Hyperspectral Stimulated Raman Scattering Microscopy," bioRxiv, 2021.
43. JM Bender, WR Adams, A Mahadevan-Jansen, WD Merryman, MR Bersi, "Radiofrequency ablation alters the microstructural organization of healthy and enzymatically digested porcine mitral valves," Experimental mechanics 61 (1), 237-251, 2021.
44. YC Ou, X Wen, CA Johnson, D Shae, OD Ayala, JA Webb, EC Lin, ..., "Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies (vol 14, pg 651, 2020)," ACS NANO 14 (12), 17714-17714, 2020.
45. YC Ou, X Wen, CA Johnson, D Shae, OD Ayala, JA Webb, EC Lin, ..., "Correction to “Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies”," ACS nano 14 (12), 17714-17714, 2020.
46. Y Sadovsky, RM Freathy, A Mahadevan-Jansen, S Mesiano, JC Murray, ..., "Reply to “Diversity is essential for good science and Reproductive science is no different: A response to the recent formulation of the Burroughs Welcome Fund Pregnancy Think-Tank”," American Journal of Obstetrics & Gynecology 223 (6), 951-952, 2020.
47. CC Solórzano, G Thomas, N Baregamian, A Mahadevan-Jansen, "Detecting the near infrared autofluorescence of the human parathyroid: hype or opportunity?," Annals of surgery 272 (6), 973, 2020.
48. M Zabolocki, K McCormack, M van den Hurk, B Milky, AP Shoubridge, ..., "BrainPhys neuronal medium optimized for imaging and optogenetics in vitro," Nature communications 11 (1), 1-19, 2020.
49. Q Liu, IM Gaeta, M Zhao, R Deng, A Jha, BA Millis, A Mahadevan-Jansen, ..., "ASIST: Annotation-free synthetic instance segmentation and tracking for microscope video analysis," arXiv preprint arXiv:2011.01009, 2020.
50. J Baba, A Mahadevan-Jansen, G Throckmorton, "Method and apparatus for intraoperative nerve visualization using polarized diffuse reflectance spectroscopy and applications of same," US Patent App. 16/851,239, 2020.
51. R Gautam, D Peoples, K Jansen, M O’Connor, G Thomas, S Vanga, ..., "Feature selection and rapid characterization of bloodstains on different substrates," Applied Spectroscopy 74 (10), 1238-1251, 2020.
52. RM Freathy, A Mahadevan-Jansen, A Moffett, ND Price, PH Wise, ..., "Special Report ajog. org," American Journal of Obstetrics & Gynecology, 2020.
53. Y Sadovsky, S Mesiano, GJ Burton, M Lampl, JC Murray, RM Freathy, ..., "Advancing human health in the decade ahead: pregnancy as a key window for discovery: a Burroughs Wellcome Fund Pregnancy Think Tank," American journal of obstetrics and gynecology 223 (3), 312-321, 2020.
54. A Abbas, M McWade, A Mahadevan-Jansen, "Optical overlay device," US Patent App. 16/752,640, 2020.
55. G Hiremath, A Locke, G Thomas, R Gautam, S Acra, H Correa, ES Dellon, ..., "Novel insights into tissue-specific biochemical alterations in pediatric eosinophilic esophagitis using raman spectroscopy," Clinical and translational gastroenterology 11 (7), 2020.
56. AI Borrachero‐Conejo, WR Adams, E Saracino, MG Mola, M Wang, ..., "Stimulation of water and calcium dynamics in astrocytes with pulsed infrared light," The FASEB Journal 34 (5), 6539-6553, 2020.
57. G Thomas, E Mannoh, ME Sanders, N Baregamian, CC Solxrzano, ..., "Applying a Fiber Probe-based Approach for Identifying Parathyroid Glands and Assessing its Vascularity During Neck Surgeries," Clinical and Translational Biophotonics, TTu4B. 6, 2020.
58. WR Adams, R Gautam, GA Throckmorton, LE Masson, JB Ford, ..., "Probing the mechanisms of infrared neural stimulation with stimulated Raman scattering microscopy (Conference Presentation)," Advanced Chemical Microscopy for Life Science and Translational Medicine …, 2020.
59. R Gautam, J Herington, N Brown, W Adam, JH Rogers, J Bateman, ..., "Comparing cervical maturation in preterm and term birth mouse models with Raman spectroscopy (Conference Presentation)," Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry …, 2020.
60. WR Adams, AI Borrachero-Conejo, E Saracino, M Wang, T Posati, ..., "Astrocyte sensitivity to pulsed infrared light: molecular, physiological, and mechanistic insights (Conference Presentation)," Optogenetics and Optical Manipulation 2020 11227, 112270N, 2020.
61. GA Throckmorton, WR Adams, ZC Ricks, JM Cayce, ED Jansen, ..., "Comparing the efficacy of infrared diode and Ho: YAG lasers for infrared neural stimulation (Conference Presentation)," Optogenetics and Optical Manipulation 2020 11227, 112270R, 2020.
62. S Fitzgerald, G Thomas, A Mahadevan-Jansen, "Nonlinear optical microscopy of lipogenesis and metabolism in HER2+ breast cancer (Conference Presentation)," Multiscale Imaging and Spectroscopy 11216, 112160D, 2020.
63. A Abbas, M McWade, A Mahadevan-Jansen, "Optical overlay device," US Patent 10,579,891, 2020.
64. R Gautam, J Herington, N Boatwright, J Rogers, W Adams, J Bateman, ..., "Evaluating Cervical Remodeling in Preterm and Term Birth Mouse Models with in vivo Raman Spectroscopy.," REPRODUCTIVE SCIENCES 27 (SUPPL 1), 66A-66A, 2020.
65. M Zhao, A Jha, Q Liu, BA Millis, A Mahadevan-Jansen, L Lu, BA Landman, ..., "Faster mean-shift: Gpu-accelerated embedding-clustering for cell segmentation and tracking," arXiv preprint arXiv:2007.14283, 2020.
66. A Locke, S Fitzgerald, A Mahadevan-Jansen, "Advances in optical detection of human-associated pathogenic bacteria," Molecules 25 (22), 5256, 2020.
67. X Wen, YC Ou, G Bogatcheva, G Thomas, A Mahadevan-Jansen, B Singh, ..., "Probing metabolic alterations in breast cancer in response to molecular inhibitors with Raman spectroscopy and validated with mass spectrometry," Chemical science 11 (36), 9863-9874, 2020.
68. B Rosal, G Thomas, A Mahadevan-Jansen, PR Stoddart, "NIR Autofluorescence: Molecular Origins and Emerging Clinical Applications," Near Infrared-Emitting Nanoparticles for Biomedical Applications, 21-47, 2020.

Bahram Javidi is Board of Trustees Distinguished Professor at University of Connecticut, the highest honor bestowed on faculty, based on research, teaching, and service. His interests are in a broad range of transformative imaging approaches using optics and photonics. He has made seminal contributions to multi-dimensional imaging from nano to macro scales. He has over 1200 publications cited over 42000 times (h-index=103) according to Google Scholar. His research has been recognized by awards from major societies, including The Optica (OSA) Emmett Leith Medal (2021), Optica C. E. K. Mees Medal (2019); IEEE William Streifer Scientific Achievement Award (2019); Optica Joseph Fraunhofer Award (2018); and European Physical Society Prize for Applied Aspects of Quantum Electronics and Optics (2015). He was awarded the IEEE Donald Fink Paper Prize (2008); John Simon-Guggenheim Foundation Fellow Award (2008); Alexander von Humboldt Foundation Prize (2007); SPIE Technology Achievement Award (2008); and SPIE Dennis Gabor Award (2005).

Federico Capasso is the Robert Wallace Professor of Applied Physics at Harvard University, which he joined in 2003 after 27 years at Bell Labs where his career advanced from postdoctoral fellow to Vice President for Physical Research. He has made contributions to optics and photonics, nanoscience, materials science, including the bandgap engineering technique leading to his invention of the quantum cascade laser, MEMS based on the Casimir effect and the first measurement of the repulsive Casimir force, research on metasurfaces including the generalized laws of refraction and reflection, “flat optics” such a high performance metalenses and Matrix Fourier optics used to demonstrate single shot ultracompact polarization sensitive cameras. He is cofounder and a board member of Metalenz (https://www.metalenz.com/), which he cofounded in 2016 and is focused on commercializing metaoptics for high volume markets.

His awards include the Yves Medal of Optica (formerly Optical Society), the Balzan Prize in Applied Photonics, the King Faisal Prize, the IEEE Edison Medal, the American Physical Society Arthur Schawlow Prize in Laser Science, the AAAS Rumford Prize, the Enrico Fermi Prize, the European Physical Society Quantum Electronics Prize, the Wetherill Medal of the Franklin Institute, the Materials Research Society Medal, the Jan Czochralski Award for lifetime achievements in Materials Science, the Rob Wood Prize of Optica. He is a member of the National Academy of Sciences, the National Academy of Engineering, the Academia Europaea, the Accademia dei Lincei, fellow of the National Academy of Inventors, and a fellow of the American Academy of Arts and Sciences (AAAS). He holds honorary doctorates from Lund University, Diderot University, University of Bologna and University of Roma, Tor Vergata.